Figure 2
From: Profiling of miRNAs and target genes related to cystogenesis in ADPKD mouse models
Correlation between cystogenesis-regulated miRNAs and candidate target mRNAs to the actin cytoskeleton. (A) Heat map of 13 differentially expressed miRNAs (DEmiRs) which were commonly changed in kidneys of both Pkd1 f/f:HoxB7-Cre and Pkd2 f/f:HoxB7-Cre mice for each time point. (B) Heat map displaying the differentially expressed mRNAs which are candidate targets of the 13 common DEmiRs from both mouse models and related with actin cytoskeleton signaling in Pkd1 f/f:HoxB7-Cre mice. (C) Interactive network between 13 DEmiRs and differentially expressed mRNAs associated with the actin cytoskeleton signaling pathway.
