Table 1 Antibacterial activities of synthetic peptides and and antibiotics.
Peptides | Sequences | M. Wa | MICb/MBCc (μM) | ||
|---|---|---|---|---|---|
Vv | St | Sa | |||
HPA3P | AKKVFKRLPKLFSKIWNWK-NH2 | 2417.2 | 8/8 | 8/8 | 16/16 |
HPA3P2 | AKKVFKRLPKLPSKIWNWK-NH2 | 2367.0 | >64/>64 | >64/>64 | >64/>64 |
A3-APO | RPDKPRPYLPRPRPPRPVR-NH2 | 2350 | >64/>64 | 32/32 | >64/>64 |
HPA3PHis | AKKVFKRLPKLFSKIWNWKHHHHHH-NH2 | 3348.1 | 8/8 | 32/32 | 16/16 |
HPA3P2His | AKKVFKRLPKLPSKIWNWKHHHHHH-NH2 | 3280.9 | 64/64 | >64/>64 | >64/>64 |
A3-APOHis | RPDKPRPYLPRPRPPRPVRHHHHHH-NH2 | 3480.7 | >64/>64 | 32/32 | >64/>64 |
Antibiotics | Classification | M. W a | MIC b /MBC c (μM) | ||
Vv | St | Sa | |||
Ampicillin | Penicillins | 349.4 | >64/>64 | 8/8 | 1/1 |
Doxycycline | Tetracyclins | 444.4 | 0.5/0.5 | 8/16 | 1/2 |
Erythromycin | Macrolides | 733.9 | 2/4 | >64/>64 | 0.5/1 |