Figure 6

Representative structures of the cytoplasmic side of the (A) inactive (in silver), (B) intermediate (in green) and (C) active (in magenta) states of P2Y₁R. P2Y₁R is displayed in cartoon, and residues Ser146^3.47, Tyr237^5.58, Val262^6.37 and Phe269^6.44 are displayed in ball-and-stick.