Figure 3

Hepatocellular carcinoma. (A) Externalized tumor. Note basophilic (purple-blue) and necrotic (pale pink) areas. Arrowheads point to small intra lobar tumors. (B) Intra lobar tumor. Note clear delimitation between tumor and normal tissue. Angiectasis is evident. (C) Tumor border. Note absence of capsule and compression of normal tissue (bracket). (D and E) Histological organization. Note that hepatocyte differentiation is maintained although some giant cells have developed (aster) and high mitotic rate (arrow). Normal histological organization is lost. (F) Necrosis and hemorrhage. H&E staining. Scale bares are indicated on pictures.