Figure 3 | Scientific Reports

Figure 3

From: 11β-hydroxysteroid dehydrogenase type 1 has no effect on survival during experimental malaria but affects parasitemia in a parasite strain-specific manner

Figure 3

11β-HSD1 has no effect on the production of malaria-specific IgG and IgM. Hsd11b1 Del/Del and WT mice were infected with PcAS. Malaria-specific antibody levels in plasma were analysed by ELISA at 21 days post-infection. Each dot represents the result from an individual mouse. Horizontal lines in between data points represent group medians and analysis was by Mann-Whitney U-test. Asterisks above individual data sets indicate statistical differences compared to the uninfected control group. Data from 2 separate experiments. n = 10 (6 F and 4 M) for WT and n = 12 (6 F and 6 M) for Hsd11b1 Del/Del. ns, not significant.

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