Figure 3 | Scientific Reports

Figure 3

From: Active Immunization Against hIAPP Oligomers Ameliorates the Diabetes- Associated Phenotype in a Transgenic Mice Model

Figure 3

Treated mice had higher insulin content and less hIAPP accumulation in the pancreas. (A) Confocal microscopy analysis of histological sections of treated mice compared with the mock group. Histological sections were stained for hIAPP (red) and insulin (green). As shown, the treated group showed higher insulin levels and lower levels of hIAPP accumulation. Scale bar 200 µm. (B) Quantification of insulin and hIAPP in immunized and mock groups (N = 4 per group), **P < 0.005.

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