Figure 1

Detection of heat production and apoptosis in tumor xenograft model. (A) Temperature calibration analysis using thermography after ICG-NIR irradiation. (B) Time course of temperature elevation after NIR irradiation with or without ICG administration. (C) Detection of apoptosis through TUNEL staining (x 400). The intranuclear staining was evaluated. Arrows indicate the cells which express a typical apoptosis.