Table 1 Participant Characteristics at study entry.

From: Effects of Supra-Physiological Levothyroxine Dosages on Liver Parameters, Lipids and Lipoproteins in Healthy Volunteers: A Randomized Controlled Crossover Study

 

Study A (n = 16)

Study B (n = 12)

Male, n (%)

9 (56.3)

6 (50.0)

Age, years, mean (range)

30.2 (25–39)

29.3 (26–40)

AST (U/L)

24 ± 3

20 ± 4

ALT (U/L)

25 ± 14

18 ± 4

ALP (U/L)

64 ± 19

65 ± 15

Gamma-GT (U/L)

19 [14–29]

16 [13–19]

Total Bilirubin (µmol/L)

9 ± 4

12 ± 8

Conjugated Bilirubin (µmol/L)

3.7 ± 1.3

4.3 ± 2.1

Total Cholesterol (mmol/L)

4.9 ± 0.9

4.3 ± 0.5

LDL-Cholesterol (mmol/L)

3.1 ± 0.8

2.8 ± 0.5

HDL-Cholesterol (mmol/L)

1.4 ± 0.4

1.2 ± 0.3

Triglycerides (mmol/L)

0.82 [0.54–1.14]

0.83 [0.73–1.14]

Apolipoprotein B (g/L)

0.88 ± 0.22

0.88 ± 0.12

Apolipoprotein A1 (g/L)

1.49 ± 0.24

1.39 ± 0.13

Lipoprotein (a) (g/L)

0.07 [0.02–0.21]

0.08 [0.04–0.33]

  1. Data represent means ± standard deviation or medians [inter quartile range]. Abbreviations: AST = aspartate aminotransferase, ALT = alanine aminotransferase, ALP = alkaline phosphatase, LDL-cholesterol = low-density lipoprotein-cholesterol, HDL-cholesterol = high density lipoprotein-cholesterol, Gamma-GT = gamma-glutamyltranspeptidase, n = number of individual.
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