Figure 1

Real-time monitoring of volatile metabolites during yeast growth; (a) raw time profiles of ethanol (detected as the dimer) and acetic acid during growth on ¹²C₆-glucose and re-injection of glucose after ~27 h; (b) normalized raw time profiles of ethanol (detected as the dimer), acetic acid and the image signal captured by a time-lapse camera during growth on ¹³C₆-glucose; c) heatmap showing 263 time-dependent signals during yeast growth. All the signals in the heatmap were labeled with ¹³C. For reference, the ethanol signal is shown on the top.