Table 1 The contents of nickel in each organ of mice 75 days exposure to different dose nickel chloride by oral administration at of 20 or 40 mg/kg/day.

From: Upregulation of microRNA-4417 and Its Target Genes Contribute to Nickel Chloride-promoted Lung Epithelial Cell Fibrogenesis and Tumorigenesis

Ni (ppb)

control group

Ni-exposed group

ddH2O

20 mg/kg/day

100 mg/kg/day

lung

86.60 ± 70.68

550.51 ± 130.25*

5739.75 ± 809.61*

kidney

60.13 ± 28.09

1298.21 ± 602.40

5615.81 ± 1581.52*

liver

27.49 ± 13.92

130.95 ± 3.29**

779.42 ± 45.79**

brain

43.37 ± 35.02

127.40 ± 21.24

798.12 ± 67.63*

spleen

203.09 ± 93.27

424.29 ± 47.36

2920.64 ± 624.81*

stomach

94.34 ± 29.22

296.92 ± 182.90

27567.55 ± 27787.24

  1. Note: Values represent mean ± SEM.
  2. *p < 0.05 and **p < 0.01, significantly different from control group.
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