Table 3 Comparison of target and OARs’ dose-volume parameters in the subgroup of centrally and peripheral located lung lesions.

From: Dosimetric comparison of the helical tomotherapy, volumetric-modulated arc therapy and fixed-field intensity-modulated radiotherapy for stage IIB-IIIB non-small cell lung cancer

   

TOMO

VMAT

IMRT

P value

T vs. V

T vs. I

V vs. I

Central

PTV

CI

0.76 ± 0.07

0.83 ± 0.06

0.76 ± 0.04

0.026

0.969

0.004

HI

0.14 ± 0.04

0.09 ± 0.02

0.10 ± 0.02

0.001

0.038

0.228

Lung

V5 (%)

43.41 ± 8.69

43.28 ± 13.26

39.12 ± 10.67

0.974

0.002

0.336

V20 (%)

21.06 ± 6.53

22.26 ± 7.48

23.38 ± 5.49

0.695

0.002

0.650

Peripheral

PTV

CI

0.77 ± 0.06

0.79 ± 0.07

0.74 ± 0.07

0.198

0.157

0.034

HI

0.14 ± 0.05

0.10 ± 0.03

0.11 ± 0.02

0.042

0.036

0.175

  1. Abbreviation: OAR = organs at risk; PTV = planning target volume; CI = conformity index; HI = heterogeneity index; T = helical tomotherapy; V = volumetric-modulated arc therapy; I = intensity-modulated radiotherapy; MLD = mean lung dose.
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