Figure 1
From: Glomerulocapillary miRNA response to HLA-class I antibody in vitro and in vivo

Representative micrographs of human glomerular endothelial cells in the in vitro model of anti-HLA class I-mediated ABMR. After incubation with (a) irrelevant anti-A1 and without complement, (b) irrelevant anti-A1followed by complement, (c) anti-A2 without complement and (d) anti-A2 followed by complement. Only the latter showed marked cytopathic changes with cytoplasmic retraction and shrinking.