Figure 2
From: Glomerulocapillary miRNA response to HLA-class I antibody in vitro and in vivo
Volcano plot of differentially regulated miRNAs in vitro upon stimulation of endothelial cells with anti-HLA-class I antibodies without complement. The x-axis shows the log2 of the fold change between in vitro C− and the control, the y-axis shows the −log10 of the p-value of a two-sided t-test. Each experiment was performed in triplicates. miRNAs that were included in the validation on microdissected glomeruli from transplant biopsies based on differential expression and validated target pathways are shown in solid dots, those excluded in gray squares.
