Figure 3
Effect of NMN and exercise on expression of genes involved in fat transport, synthesis and β-oxidation in liver. Data are shown as mean ± SEM, n = 9–10 per group. The first letter represents maternal and second letter represents post-weaning diet; chow (C) or HFD (H); the third letter represents intervention; sedentary (S), exercise (X) or NMN (N). Data are presented as fold changes compared to the CCS group. To investigate the effects of post-weaning diets and intervention (exercise and NMN) on mRNA expression of Cd36 (A), Fasn (B), Acc1 (C), Acc2 (D), Pparg (E), Mpc1 (F), Hadh (G) of the offspring of obese mothers consuming chow or HFD, HCS, HCX, HCN and HHS, HHX, HHN were compared by separate two-way ANOVAs. The significant effects are: ***P < 0.001 overall post-weaning diet effect. #P < 0.01 and ###P < 0.001 overall intervention effect. XP < 0.05 and XXXP < 0.001 simple main effect of exercise. ^P < 0.05; ^^P < 0.01 and ^^^P < 0.01 simple main effect of NMN.
