Figure 6
From: Efficacy of an Adenoviral Vectored Multivalent Centralized Influenza Vaccine
Protection Against Lethal H5N1 Influenza Virus Using a Multivalent Centralized H1, H2, H3 and H5 Vaccine. Mice that were vaccinated with various doses of the multivalent vaccine expressing all four consensus HA genes were challenged with 100 MLD50 of mouse-adapted influenza A/Vietnam/1203/04 (A), A/BH Goose/Qinghai/A/05 (B) and A/Japanese White Eye/Hong Kong/1038/2006 (C). The mice were monitored for weight loss, disease and survival. Mice that lost ≥ 25% of their baseline weight were humanely euthanized.
