Figure 2

The 3D-structure of the BoNT/A and BoNT/E peptide substrates with the BoNT/A catalytic domain. (A) SNAP-25 fragment 167–204. The BoNT/A substrate is marked in red, BoNT/E substrate is marked in green and overlapping sequence is marked in orange. (B) The overlapping region of the two substrates is highlighted as orange spheres.