Figure 8
Linearity of the assay for BoNT/B and BoNT/E. 0.5–10 MsLD50/ml of BoNT/B (A) or BoNT/E (B) was analysed. Cleavage products were analysed by LC-MS/MS. Data are presented on a logarithmic scale. The experiments were repeated 2–3 times. The R2 values of the N- and C-terminal products were 0.99 and 0.99 for BoNT/B and 0.97 and 0.99 for BoNT/E, respectively (P < 0.001 and P = 0.001 for the N and C-terminal fragment of BoNT/B and P = 0.03 and P = 0.007 for the N and C-terminal fragment of BoNT/E, respectively).
