Figure 2

Gyrification index differences between newborns with complex congenital heart disease (open blue) and healthy controls (solid orange), in the whole brain (a) and exploratory regional analysis (b–e). The cortical surface visualisation (f) demonstrates regions where gyrification is reduced in newborns with congenital heart disease compared to healthy term controls, from the left lateral side (i) and from above (ii); colours represent p values from multivariate general linear models, using postmenstrual age as a covariate; no multiple comparisons correction has been performed in this visualisation.