Table 1 Cohort characteristics.

From: Impaired development of the cerebral cortex in infants with congenital heart disease is correlated to reduced cerebral oxygen delivery

Variable

Control Newborns n = 30

Newborns with Congenital Heart Disease n = 30

p value

Gestational age at birth (weeks)

38.9 (38.1–39.3)

38.4 (37.9–38.9)

0.07

Post-menstrual age at scan (weeks)

39.1 (38.7–39.7)

39.3 (38.7–39.6)

0.81

Male

16

8

0.06

Birth weight (g)

3220 (2920–3550)

3125 (2800–3500)

0.37

Birth weight z-score

−0.02 (−0.39–0.5)

−0.17 (−0.77–0.49)

0.69

Birth head circumference (cm)

34.5 (33–35.5)

34 (33–35)

0.24

Birth head circumference z-score

0.72 (−0.06–1.20)

0.05 (−0.49–0.76)

0.11

Heart lesion – no. (%)

- Transposition of the great arteries (TGA)

14 (47)

 

   - TGA requiring septostomy (% TGA)

 

5 (36)

 

- Coarctation of the aorta

4 (13)

 

- Hypoplastic left heart syndrome

3 (10)

 

- Pulmonary atresia

3 (10)

 

- Tetralogy of Fallot

3 (10)

 

- Pulmonary stenosis

2 (7)

 

- Truncus arteriosus

1 (3)

 
  1. GA at birth and PMA at scan are presented as median (interquartile range). Apgar scores reflect condition at birth, ranging from 0 to 10, with lower scores indicating a worse clinical condition. p values calculated using Mann–Whitney U test for continuous data, and Fisher’s exact test for categorical variables. z-scores for head circumference and birth weight calculated using UK-WHO 2006 reference data.