Figure 6 | Scientific Reports

Figure 6

From: Metoprolol prevents chronic obstructive sleep apnea-induced atrial fibrillation by inhibiting structural, sympathetic nervous and metabolic remodeling of the atria

Figure 6

Expression of proteins involved in the Sirt1/AMPK pathway in hypoxic HL-1 cells. (A) Representative bands and statistical results for the protein expression of p-Sirt1 in HL-1 cells. (B) Representative bands and statistical results for the protein expression of Sirt1 in HL-1 cells. (C) Representative bands and statistical results for the protein expression of p-AMPK in HL-1 cells. (D) Representative bands and statistical results for the protein expression of AMPK in HL-1 cells. (E) Representative bands and statistical results for the protein expression of HIF-1α in HL-1 cells.The expression levels of these proteins were normalized to the level of GAPDH. *p < 0.05, **p < 0.01, ***p < 0.001 vs Normoxia group, # p < 0.05, ## p < 0.01, ### p < 0.001 vs the ISO + MET group, n = 4 each group.

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