Table 1 Neurotoxins of the C. japonicus sea anemone. Length (in number of aa residues) is shown for mature sequences.

From: Identification of unusual peptides with new Cys frameworks in the venom of the cold-water sea anemone Cnidopus japonicus

Toxin

Length

Homolog

E-value

Identity

Organism

Cys-framework

Superfamily

AnmTX Cj 3a-1

70

APEKTx1

2e–15

46%

Anthopleura elegantissima

3a

Kunitz-type

AnmTX Cj 3a-2

59

Chymotrypsin inhibitor (P00992)

1e–14

55%

Vipera ammodytes

3a

Kunitz-type

AnmTX Cj 1a-1

48

Gigantoxin-III

6e–09

50%

Stichodactyla gigantea

1a

NaTX Type II

AnmTX Cj 1c-1

49

Gigantoxin-II

1e–05

52%

S. gigantea

new (1c)

NaTX Type I

AnmTX Cj 1b-1

46

BDS-I

4e–4

48%

Anemonia sulcata

1b

KTX type III

AnmTX Cj 8a-1

66

AETX III

2e–3

36%

Anemonia erythraea

8a

—

AnmTX Cj 8a-2

71

AETX III

0.027

37%

A. erythraea

8a

—

AnmTX Cj 6a-1

41

Acrorhagin Ia

0.880

29%

Actinia equina

6a

—

  1. The E-value is taken from pBLAST results. The species from which the closest homologue was isolated, the Cys framework motif, and the superfamily in UniProt are shown. A light grey background marks the polypeptides that have a new cysteine distribution motif.