Figure 3 | Scientific Reports

Figure 3

From: Interplay between trauma and Pseudomonas entomophila infection in flies: a central role of the JNK pathway and of CrebA

Figure 3

Impact of Jra/dJun modulation of expression on survival of SH and DH flies. Sterile wounding and/or Pe infection were performed on 1 week old adult females of Tubulin > GeneSwith/+; UAS-dJun RNAi/+ (Jra/dJun RNAi, (a,b) and Tubulin > GeneSwith/+; UAS-Jra/+ (Jra/dJun overexpression) genotypes in the absence (a,c: not induced) or in the presence (b,d: induced) of RU486 at indicated concentrations. Fly survival was surveyed up to 50 hours after treatments. (a,b) Jra/dJun inhibition improved the survival of DH flies but did not impact that of SH ones (see also Supplementary Figure S3). (c,d) Jra/dJun overexpression was deleterious for both DH and SH flies (see also Supplementary Figure S3). Each group consisted of 120 flies observed among 3 different experiments (40 flies/group/experiment). Statistical analyses were performed using the Log Rank test method (**P < 0.01; ***P < 0.001). Means of survival are shown, and error bars represent standard deviations.

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