Figure 3
From: Mutation accumulation under UV radiation in Escherichia coli
Viability and mutability of evolved strains in response to UV exposure. Survival rate (a) and NalR mutant fraction (b) in response to UV exposure are shown for the final populations in the evolution experiment and their ancestral strains. UV doses of 5 and 10 mJ/cm2 were used for Co and ΔS, while 0.6 and 1.2 mJ/cm2 were used for ΔHSB. The mean values were calculated for six lineages of each evolved strain. The error bars represent standard deviations. Asterisks indicate that the survival rates or mutation fractions significantly increased (single asterisks) or decreased (double asterisks) compared to the ancestors after evolution (t-test or Mann-Whitney U test, FDR < 0.05, see Methods). (c) Scatter plots of survival rates and NalR mutant fractions of the ancestral strains (black circles), the lineages with/without UV exposure during evolution experiment (purple/grey circles, respectively). The values were replotted from (a) and (b). The vertical/horizontal dashed lines indicate the values of the ancestral strains.
