Figure 2 | Scientific Reports

Figure 2

From: In vivo characterization of the electrophysiological and astrocytic responses to a silicon neuroprobe implanted in the mouse neocortex

Figure 2

No increase in astrocyte response from week 2 to week 10 post implantation. (a) Time-lapse images of the same field of view for 10 consecutive weeks. Example images taken 200 µm below pia (M3). Scale bars indicate 100 µm. (b) Histogram of pixel intensities of images acquired in M3 on week 5 with pixel intensity cutoff (yellow) used to delineate the region of interest for calculating the average intensities reported in c. (c) Normalized fluorescence intensity in region of interest for each experimental session for 3 mice over 10 weeks. Fluorescence intensity normalized by median intensity from week 2 to week 10. Note how Aldh1l1-GFP expression remains stable over time.

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