Table 3 Lupus nephritis patient demographic data and clinical scores.

From: Transcriptomic profiling in human mesangial cells using patient-derived lupus autoantibodies identified miR-10a as a potential regulator of IL8

Characteristics

Active LN

Healthy Controls

P-value

Number

20

20

NA

Sex (F/M)

19/1

19/1

NA

Age (average, s.d.)

33.75, 8.52

38.3, 8.93

0.1518

Clinical parameters (average, s.d.)

Serum creatinine (mg/dL)

1.002, 0.1065

NA

NA

Proteinuria (g/day)

3.081, 0.3996

NA

NA

Urinary Erythrocyte Count (/HPF)

10.55, 4.863

NA

NA

MDRDa GFR (mL/min)

82.08, 7.259

NA

NA

LN Renal Histology

Class III

1/20

NA

NA

Class IV

11/20

NA

NA

Class V

2/20

NA

NA

Class III + V

1/20

NA

NA

Class IV + V

5/20

NA

NA

Activity index (average, s.d.)

5.9, 3.63

NA

NA

Chronicity index (average, s.d.)

5.2 ± 3.85

NA

NA

Steroid dose (mg/day) (average, s.d.)

19.63 ± 2.829

NA

NA

  1. F, female; M, male; NA, not available; s.d., standard deviation; GFR, glomerular filtration rate; MDRD, The Modification of Diet in Renal Disease; HPF, high power field; LN, Lupus nephritis.
  2. aThe equation to calculate estimate glomerular filtration rate for Thais is 375.5 × serum Creatinine (āˆ’0.848) × age (āˆ’0.364) × 0.712 (if female).