Figure 1

Perinatal exposure to BPA provokes metabolic disorders in offspring male mice. (a) Body weight of BPA and vehicle mice was measured from PND21 to PND170. (b) Perigonadal WAT weight of BPA and vehicle offspring was determined at PND45 and PND170. (c) Glucose and insulin tolerance tests were performed at PND35 and 125 respectively. The Quantitative Insulin Sensitivity Check Index (QUICKI) was calculated at PND160. Data represent the mean ± s.e.m. (n = 10–16). Data were representative from two batches of experiments. *P < 0.05, **P < 0.01, vs. non-exposed group using a Mann-Whitney’s post-hoc analysis.