Figure 4 | Scientific Reports

Figure 4

From: Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice

Figure 4

Pentose phosphate pathway (PPP) is altered in the β–carotene oxygenase 2 (BCO2) knockout (KO) liver. (A–F) Metabolites associated with PPP. (G) Simplified scheme about PPP in the liver. Values are means ± SD. Data was analyzed by one-way ANOVA. n = 6. Different letters indicate significant difference between groups. P-value ≤ 0.05 is considered as significant. F-1,6-BP, fructose-1,6-bisphosphate; DHAP, dihydroxyacetone phosphate; G-6-P, glucose 6-phosphate; 6-PG, 6-phosphogluconate; G-3-P, glyceraldehyde 3-phosphate; PEP, phosphoenolpyruvate; TCA cycle, the tricarboxylic acid cycle; OXPHOS, oxidative phosphorylation; WT, wild type; Het, BCO2 heterozygous mice; KO, BCO2 knockout mice.

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