Figure 4

The hypothetical incomplete regulation of pathways during the reprogramming of hiPSCs. (a) Down-regulation in hiPSCs/HFF and hESCs/HFF and up-regulation in hiPSCs/hESCs suggest an incomplete repression of pathways. (b) Up-regulation in hiPSCs/HFF and hESCs/HFF and down-regulation in hiPSCs/hESCs suggest an incomplete activation of pathways.