Table 1 Significant pathways of hiPSCs/HFF and hESCs/HFF.
Pathway | hiPSCs/HFF (p-val/FDR) | hESCs/HFF (p-val/FDR) |
|---|---|---|
REACTOME: platelet activation signaling and aggregation | DOWN 0.000/0.000 | DOWN 0.000/0.000 |
REACTOME: hemostasis | DOWN 0.000/0.002 | DOWN 0.000/0.007 |
REACTOME: adaptive immune system | DOWN 0.002/0.003 | DOWN 0.002/0.002 |
REACTOME: immune system | DOWN 0.000/0.003 | DOWN 0.002/0.006 |
KEGG: regulation of actin cytoskeleton | DOWN 0.000/0.000 | DOWN 0.000/0.000 |
KEGG: focal adhesion | DOWN 0.000/0.000 | DOWN 0.000/0.001 |
KEGG: leukocyte transendothelial migration | DOWN 0.101/0.132 | DOWN 0.060/0.088 |
REACTOME: axon guidance | DOWN 0.000/0.004 | DOWN 0.000/0.010 |
REACTOME: developmental biology | DOWN 0.002/0.003 | DOWN 0.002/0.009 |
REACTOME: TCA cycle and respiratory electron transport | UP 0.000/0.004 | UP 0.000/0.001 |
KEGG: oxidative phosphorylation | UP 0.000/0.001 | UP 0.000/0.000 |
KEGG: Alzheimer’s disease | UP 0.159/0.196 | UP 0.084/0.074 |
KEGG: Huntington’s disease | UP 0.000/0.001 | UP 0.000/0.000 |
KEGG: tight junction | DOWN 0.222/0.214 | N/A— |
REACTOME: respiratory electron transport ATP synthesis by chemiosmotic coupling and heat production by uncoupling proteins | UP 0.000/0.003 | N/A— |
KEGG: Parkinson’s disease | UP 0.000/0.001 | N/A— |
REACTOME: post-translational protein modification | UP 0.004/0.020 | N/A 0.224/0.601 |
REACTOME: metabolism of proteins | UP 0.002/0.039 | N/A 0.088/0.694 |
REACTOME: asparagine N-linked glycosylation | UP 0.105/0.204 | N/A 0.534/0.626 |
