Table 1 Clinical characteristics of the study population.

From: Impact of Lactobacillus reuteri colonization on gut microbiota, inflammation, and crying time in infant colic

Characteristic

Original trial16

This study

Probiotic (n = 85)

Placebo (n = 82)

Colonized by L. reuteri (n = 14)

Not colonized by L. reuteri (n = 51)

P-valuea

Gender Male, n (%)

37 (44)

48 (59)

6 (43)

30 (59)

0.29b

Mode of birth Caesarean section, n (%)

35 (41)

32 (39)

4 (29)

20 (40)

0.46b

Method of feeding Exclusively breastfed, n (%)

33 (39)

35 (43)

6 (43)

17 (33)

0.51b

Family history of allergic disease Yes, n (%)

51 (60)

50 (61)

11 (79)

41 (80)

0.88b

Birth weight (g) Mean ± SD

3272 ± 406

3426 ± 421

3425 ± 482

3312 ± 398

0.57c

Infant age at enrolment (weeks) Mean ± SD

7.5 ± 2.9

6.9 ± 2.5

8.2 ± 2.8

7.4 ± 2.7

0.29c

Infant crying time at day 0 (min/day) d Mean ± SD

327.6 ± 151.9

329.3 ± 126.4

337.2 ± 186.3

344.1 ± 124.1

0.94c

  1. aDifferences assessed for infants in the current study (colonized versus not colonized by L. reuteri). bChi-Squared test; c Mann-Whitney U test; dCalculated using probiotic (n = 75), placebo (n = 65), colonized by L. reuteri (n = 13), and not colonized by L. reuteri (n = 47) due to missing data.
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