Table 1 Differences in the number of ∆FOSB-positive cells between defeated and control mice in each brain region of interest.

From: Brain activation induced by chronic psychosocial stress in mice

Brain region

Full name

N control

N defeated

% change +

t/U

P

MO

Medial orbital cortex

7

7

+39.7

1.072 (t)

0.315

IL

Infralimbic cortex

7

8

+109.1

1.801 (t)

0.095

PrL

Prelimbic cortex

7

8

+66.9

1.536 (t)

0.148

BNST

Bed nucleus of stria terminalis (anterodorsal)

6

7

+306.4

2.644 (t)

0.034

AcbC

Nucleus accumbens (core)

7

8

+139.4

1.389 (U)

0.189

AcbSh

Nucleus accumbens (shell)

6

8

+82.3

0.645 (U)

0.573

CPu

Caudate putamen

7

8

+753.7

2.083 (U)

0.006

LSV

Lateral septum (ventral)

7

8

+89.0

2.142 (t)

0.035

VL

Thalamus (ventrolateral)

6

7

n/a

2.448 (U)

0.035

LH

Lateral hypothalamus

6

7

+153.1

2.436 (t)

0.033

BLA

Basolateral amygdala

6

7

+54.2

0.886 (t)

0.394

BMA

Basomedial amygdala

6

7

+73.5

1.206 (t)

0.253

CeA

Central amygdala

6

7

+83.7

1.410 (t)

0.186

vHP

Ventral hippocampus (CA1 & CA3)

7

8

+261.5

2.083 (U)

0.040

DG

Dentate gyrus (ventral)

6

6

+153.4

2.695 (t)

0.032

PAG

Periaqueductal grey (dorsolateral)

7

8

+112.8

1.582 (t)

0.138

VTA

Ventral tegmental area

6

6

−22.7

0.601 (t)

0.561

Pir

Piriform cortex

7

8

+16.1

0.401 (t)

0.695

  1. The number of positive cells between control and defeated mice was compared with either an independent Student’s t-test (normally distributed data, indicated with t) or a Mann-Whitney U-test (non-normally distributed data, indicated with U). N = number of animals, P = nominal p-value, +change in mean number of stained cells in defeated mice compared to controls in percentage points. Significant p-values (<0.05) which also survive correction for multiple comparisons (false discovery rate < 20%) are marked in bold.