Table 2 Common stroke scale test and blood biomarker detection results.

From: The positive effects of Xueshuan Xinmai tablets on brain functional connectivity in acute ischemic stroke: a placebo controlled randomized trial

 

Placebo group (n = 20)

Treatment group (n = 22)

Main effect of time

Main effect of group

Interaction

Baseline

2 weeks later

Baseline

2 weeks later

F value

P value

F value

P value

F value

P value

NIHSS

5.85(3.28)

3.65(2.80)

6.64(3.09)

3.23(2.41)

0.079

0.780

0.079

0.780

5.402

0.026*

Barthel

68.50(26.01)

80.75(19.49)

66.82(26.07)

67.62(25.74)

0.563

0.458

0.026

0.872

1.661

0.205

mRS

2.80(1.28)

2.00(1.33)

3.18(1.18)

1.73(1.32)

2.069

0.159

0.043

0.837

4.038

0.052

SSQOL

147.35(41.47)

189.40(37.97)

125.05(43.63)

204.05(44.27)

1.466

0.234

0.024

0.877

9.755

0.003**

Infarct volume

43280.70 (26358.07)

48388.95 (29839.52)

41005.36 (20465.21)

38572.29 (20386.29)

1.470

0.212

0.039

0.845

1.365

0.250

Fibrinogen

2.83(0.50)

2.75(0.52)

3.26(0.99)

9.26(1.12)

0.116

0.736

2.506

0.122

0.042

0.838

Hematocrit

39.09(4.72)

39.54(4.53)

39.70(4.41)

38.53(3.54)

3.978

0.054

0.001

0.980

4.601

0.039*

Total cholesterol

5.00(1.39)

4.67(0.99)

4.64(1.22)

4.34(0.98)

2.222

0.145

2.205

0.333

0.02

0.888

Triglyceride

1.81(1.99)

1.92(1.97)

1.91(1.00)

1.85(0.95)

0.013

0.909

0.131

0.719

0.948

0.336

Low-density lipoprotein

3.00(0.90)

2.77(0.67)

2.76(0.96)

2.54(0.68)

0.900

0.349

1.572

0.218

0.005

0.942

High-density lipoprotein

1.41(0.57)

1.22(0.25)

1.10(0.20)

1.17(0.27)

2.406

0.129

4.081

0.051

2.056

0.160

  1. Values are mean (SD) or number of patients. NIHSS: National Institute of Health Stroke Scale; mRS: Modified Rankin Scale; SSQOL: Stroke-Specific Quality of Life Scale; * P < 0.05, ** P < 0.01.