Figure 5
From: NF-κB Protects NKT Cells from Tumor Necrosis Factor Receptor 1-induced Death
Fas-deficiency fails to rescue NKT cell development in IκBαΔNtg. (A) Thymic, splenic and hepatic NKT cells from B6-wt/lpr (n = 2), B6-lpr/lpr (n = 2), B6-wt/lpr;IκBαΔN tg (n = 2) and B6-lpr/lpr;IκBαΔN tg (n = 2) mice were identified as CD3ε+tetramer+ cells within electronically gated CD8lo thymocytes or B220lo splenocytes. Numbers are % NKT cells among total leukocytes in each organ. (B) Absolute cell numbers were calculated from % NKT cell and total cell count. n, as in A. Data are mean ± sem from two independent experiments. ns, not significant (P > 0.05), *P ≤ 0.05.
