Figure 6 | Scientific Reports

Figure 6

From: Hypoxia-induced reactive oxygen species mediate N-cadherin and SERPINE1 expression, EGFR signalling and motility in MDA-MB-468 breast cancer cells

Figure 6

ROS scavenging with NAC reduces cell migration under hypoxic conditions. MDA-MB-468 cells were treated with NAC and exposed to hypoxia. Cell migration was analysed from 24 h to 36 h under hypoxic conditions. (A) Spatial plot of all cells from representative wells from the same experiment and (B) quantitative analysis of the mean accumulated distance travelled by cells from three independent experiment (duplicate wells) treated with NAC compared to the control cells without NAC treatment. *p < 0.05, (paired t-test).

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