Figure 5
From: α subunits in GABAA receptors are dispensable for GABA and diazepam action
Influence of different point mutations on the potentiation by diazepam. Receptors were expressed in Xenopus oocytes and first exposed to 7 µM GABA alone or the same concentration of GABA in the presence of 1 µM diazepam and the elicited current amplitude was determined. Current potentiation by diazepam was calculated and averaged for each subunit combination. Data are expressed as mean ± S.E.M., n = 4–15 from two batches of oocytes.
