Table 2 Descriptions and GO term classification of the differentially expressed genes related to immune response for CMC_DLB1-NNV vs CMC_DLB1 comparison.
Description | Gene ontology terms | CMC_DBL1 vs CTRL | CMC_DBL1-NNV vs CTRL | CMC_DBL1-NNV vs CMC_DBL1 |
|---|---|---|---|---|
histone h2a-like | response to bacterium, cell killing | not significant | not significant | up |
fc receptor-like b-like | type IIa hypersensitivity, type III hypersensitivity, antibody-dependent cellular cytotoxicity, response to bacterium, positive regulation of acute inflammatory response to antigenic stimulus, positive regulation of myeloid leukocyte mediated immunity | not significant | up | up |
arachidonate 5-lipoxygenase-activating protein (ALOX5AP) | leukotriene production involved in inflammatory response, arachidonic acid metabolite production involved in inflammatory response | up | up | up |
histone partial | response to bacterium, cell killing | not significant | up | up |
mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) | B-1 B cell differentiation, positive regulation of NF-kappaB transcription factor activity | up | up | up |
neural precursor cell developmentally down-regulated 4 (NEDD4) | cytokine-mediated signaling pathway, immune response, viral process, leukocyte activation, transmission of virus, T cell aggregation, lymphocyte aggregation, dissemination or transmission of symbiont from host, leukocyte cell-cell adhesion | up | not significant | down |
integrin alpha-4-like (ITGA4) | leukocyte cell-cell adhesion, immune system process, T cell migration, lymphocyte migration | not significant | down | down |
pleckstrin homology domain-containing family a member 1-like (PKHA1) | immune system process, antigen receptor-mediated signaling pathway | up | not significant | down |
interferon- double-stranded rna-activated protein kinase-like (PKR) | cytokine production, viral process, immune response, evasion or tolerance by virus of host immune response, regulation of NLRP3 inflammasome complex assembly, regulation of hematopoietic stem cell proliferation, response to interferon-alpha | up | up | down |
suppressor of cytokine signaling 6 (SOCS6) | leukocyte cell-cell adhesion, lymphocyte activation, immune system process, T cell aggregation, T cell activation | not significant | down | down |
semaphorin-7a-like isoform ×1 (SEMA7A) | immune system process, cytokine production, regulation of macrophage cytokine production | up | not significant | down |
bone morphogenetic protein receptor type-2 (BMPR2) | lymphatic endothelial cell differentiation | down | down | down |
Poly(ADP-ribose) polymerase family member 14 (PARP14) | T cell aggregation, T cell activation, cytokine production, viral process, regulation of immune response, interleukin-27-mediated signaling pathway, negative regulation of interleukin-6-mediated signaling pathway, regulation of defense response | not significant | not significant | down |
receptor-type tyrosine-protein phosphatase c-like (PTPRC) | immune system process, antigen receptor-mediated signaling pathway | not significant | down | down |
unconventional myosin-ie (MYO1E) | immune system process | down | down | down |
cell adhesion molecule 4-like | immune system process, cytokine production | up | up | down |
nucleic acid binding protein | lymphocyte activation, T cell migration, immune system process, T cell aggregation, T cell activation, cytokine production, viral process | up | up | down |
protein nlrc3-like | leukocyte cell-cell adhesion, immune system process, T cell migration, lymphocyte migration, T cell activation | up | not significant | down |
