Table 4 In silico prediction for oral toxicity in rodents by PROTOX.

From: Inhibition activity of a traditional Chinese herbal formula Huang-Lian-Jie-Du-Tang and its major components found in its plasma profile on neuraminidase-1

Compound

Predicted oral LD50 (mg/kg)

Prediction accuracy

Baicalein

3919

71%

Baicalin

5000

69%

Berberine

1000

100%

Coptisine

1000

73%

Epiberberine

1000

73%

Geniposide

2000

71%

Jatrorrhizine

410

69%

Oroxylin A

4000

71%

Oroxylin A 7-O-β-D-glucuronide

5000

69%

Palmatine

410

69%

Phellodendrine

2803

73%

Wogonin

3919

100%

Wogonoside

5000

69%

Zanamivir

5000

54%

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