Figure 3
From: A Feline HFpEF Model with Pulmonary Hypertension and Compromised Pulmonary Function
LV hypertrophy. HW/BW ratio (a), CM cross-sectional area (b), and ACTA1 expression levels measured by Real-Time PCR (c), were increased in banded vs sham cats. Confocal micrographs of LV tissue section stained for WGA (green) and DAPI (blue) show increased CM size and extracellular matrix deposition in banded cats (e–f) compared to sham (d). Scale bars = 50 µm. *p < 0.05, ***p < 0.001 between groups. ACTA1 = skeletal muscle actin, BW = body weight, CM = cardiomyocyte, HW = heart weight.
