Table 2 Univariable Cox proportional hazard regression analysis for predictors of 30-day mortality.

From: Usefulness of the delta neutrophil index to predict 30-day mortality in patients with ST segment elevation myocardial infarction

Variables

Univariable cox proportional hazard regression

HR (95% CI)

p-value

Male sex (vs female)

0.511 (0.325–0.804)

0.004*

Body mass index (per 1 kg/m²)

0.954 (0.895–1.017)

0.147

Use of LMWH

0.530 (0.074–3.808)

0.528

Use of unfractionated heparin

0.137 (0.043–0.434)

<0.001*

GRACE score (per 1 point)

1.031 (1.025–1.036)

<0.001*

Age (per 1 year)

1.057 (1.037–1.076)

<0.001*

Heart rate (per 1 beat/min)

1.001 (0.993–1.010)

0.801

SBP (per 1 mmHg)

0.982 (0.978–0.986)

<0.001*

Creatinine (per 1 mg/dL)

1.183 (1.082–1.294)

<0.001*

Troponin-T (per 10^3 pg/mL)

1.274 (1.190–1.364)

<0.001*

Arrest on admission

8.657 (4.693–15.967)

<0.001*

Killip class

I

Reference (1.000)

 

II

1.061 (0.369–3.053)

0.913

III

7.145 (3.499–14.587)

<0.001*

IV

10.266 (5.309–19.853)

<0.001*

Clinical measurements

LVEF (per 1%)

0.900 (0.885–0.915)

<0.001*

NT-proBNP (per 10^3 pg/mL)

1.042 (1.029–1.055)

<0.001*

Creatine kinase-MB (per 1 ng/mL)

1.004 (1.003–1.006)

<0.001*

White blood cell count (per 10^3/μL)

1.056 (1.008–1.107)

0.022*

Neutrophil ratio (per 1%)

1.009 (0.996–1.022)

0.198

hs-CRP (per 1 mg/L)

1.002 (0.999–1.005)

0.188

aPTT (per 1 sec)

1.005 (1.000–1.010)

0.065

Platelets (per 10^3/μL)

0.997 (0.994–1.000)

0.036*

Total cholesterol (per 1 mg/dL)

0.992 (0.987–0.997)

<0.001*

Triglyceride (per 1 mg/dL)

0.997 (0.993–1.001)

0.104

Glucose (per 1 mg/dL)

1.004 (1.003–1.006)

<0.001*

Medical History

Hypertension

1.125 (0.734–1.723)

0.590

Diabetes mellitus

1.692 (1.094–2.618)

0.018*

COPD

1.167 (0.287–4.745)

0.829

Hyperlipidaemia

0.480 (0.195–1.186)

0.112

History of PCI

0.936 (0.484–1.810)

0.844

CAOD

1.623 (0.991–2.657)

0.054

Heart failure

1.464 (0.463–4.635)

0.516

Arrhythmia

0.471 (0.066–3.381)

0.454

Stroke

3.400 (1.846–6.261)

<0.001*

PAOD

1.768 (0.435–7.187)

0.426

Malignancy

2.079 (1.042–4.149)

0.038*

Chronic kidney disease

2.216 (1.111–4.421)

0.024*

Chronic liver disease

1.431 (0.199–10.276)

0.722

Procedural characteristics

Door-to-balloon time (per 1 min)

1.006 (1.002–1.010)

<0.001*

Procedure time (per 1 min)

1.013 (1.007–1.020)

<0.001*

Type of contrast medium

Iopamidol

Reference (1000)

 

Iodixanol

0.921 (0.562–1.508)

0.743

Iopromide

4.710 (0.633–35.021)

0.13

Contrast volume (per 1 mL)

0.999 (0.996–1.002)

0.501

Multivessel disease

1.869 (1.150–3.036)

0.012*

LM artery involvement

2.915 (1.507–5.640)

0.002*

DNI Time-0 (per 1%)

1.165 (1.096–1.239)

<0.001*

DNI Time-I (per 1%)

1.118 (1.101–1.136)

<0.001*

DNI Time-24 (per 1%)

1.092 (1.079–1.106)

<0.001*

  1. HR, hazard ratio; CI, confidence interval; LMWH, low molecular weight heparin; GRACE, Global Registry of Acute Coronary Events; SBP, systolic blood pressure; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-brain natriuretic peptide; hs-CRP, high-sensitivity C-reactive protein; aPTT, activated partial thromboplastin time; COPD, chronic obstructive pulmonary disease; PCI, Percutaneous Coronary Intervention; CAOD, coronary artery occlusive disease; PAOD, peripheral arterial occlusive disease; LM, left main coronary artery; DNI, delta neutrophil index. *P < 0.05.
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