Table 1 Correlation matrix for PPCPs and mean neurotransmitter concentrations detected in goldfish plasma. Pearson r correlation coefficients in bold font were significantly correlated (p-value < 0.05).

From: Reduced anxiety is associated with the accumulation of six serotonin reuptake inhibitors in wastewater treatment effluent exposed goldfish Carassius auratus

 

Pearson r correlation coefficient

p-value

Aspartate

GABA

Glutamate

Histamine

Serine

Serotonin

Aspartate

GABA

Glutamate

Histamine

Serine

Serotonin

ΣAmitriptyline

0.3465

−0.0359

0.2374

−0.8390

−0.9851

0.9809

0.6535

0.9641

0.7626

0.1610

0.0149

0.0191

Caffeine

0.8506

0.5832

0.7970

−0.7159

−0.6817

0.8701

0.1494

0.4168

0.2030

0.2841

0.3183

0.1299

Citalopram

0.4167

−0.1165

0.2721

−0.9894

−0.9354

0.9274

0.5833

0.8835

0.7279

0.0106

0.0646

0.0726

DEET

0.5003

0.0257

0.3736

−0.9552

−0.9553

0.9835

0.4997

0.9743

0.6264

0.0448

0.0447

0.0165

Diphenhydramine

0.5459

0.0324

0.4118

−0.9872

−0.9088

0.9462

0.4541

0.9676

0.5882

0.0128

0.0912

0.0538

Erythromycin-H2O

0.0068

0.1584

0.0361

−0.0206

−0.4586

0.4691

0.9932

0.8416

0.9639

0.9794

0.5414

0.5309

Flumequine

0.9659

0.7950

0.9476

−0.5418

−0.4168

0.6706

0.0341

0.2050

0.0524

0.4582

0.5832

0.3294

ΣFluoxetine

0.7704

0.3404

0.6689

−0.9080

−0.7964

0.9245

0.2296

0.6596

0.3311

0.0920

0.2036

0.0755

Gemfibrozil

0.3044

0.0995

0.2424

−0.6084

−0.8788

0.8988

0.6956

0.9005

0.7576

0.3916

0.1212

0.1012

Hydrocortisone

−0.2168

−0.1760

−0.2278

−0.1385

−0.5993

0.5130

0.7832

0.8240

0.7722

0.8615

0.4007

0.4870

Iopamidol

0.5970

0.1352

0.4780

−0.9490

−0.9181

0.9807

0.4030

0.8648

0.5220

0.0510

0.0819

0.0193

Oxazepam

0.4621

0.5238

0.5096

0.2035

0.6348

−0.4510

0.5379

0.4762

0.4904

0.7965

0.3652

0.5490

Sertraline

0.8920

0.6261

0.8414

−0.7041

−0.6311

0.8349

0.1080

0.3739

0.1586

0.2959

0.3689

0.1651

Sulfamethazine

0.6926

0.3319

0.6048

−0.8443

−0.8596

0.9735

0.3074

0.6681

0.3952

0.1557

0.1404

0.0265

Venlafaxine

0.9572

0.7012

0.9144

−0.6620

−0.5090

0.7404

0.0428

0.2988

0.0856

0.3380

0.4910

0.2596