Figure 5

Phylogenetic analysis of thioester-containing proteins. Phylogenetic tree was constructed by Neighbor-joining method, using the program Mega 5.10. The bootstrap values greater than 0.5 l are presented on the nodes. The first two letters in each of the serpins represent the acronym of scientific name for a given species. The GenBank accession number for sequences used in phylogenetic analysis in Fig. 5: AaTep (EAT39604.1, Aedes aegypti); AgTep (AAG00600.1, Anopheles gambiae); AmTepA, AmTepB, AmTep7 (XP_397416.3, GB1260528, XP_006565503.1, Apis melliferal); BbC3 (AB050668.1, Branchiostoma belcheri); BfCPAMD8 (XP_002586872.1, Branchiostoma floridae), CiCPAMD8, CiC3 (XP_009861615.2, NP_001027684.1, Ciona intestinalis); CrC3 (AAQ08323.1, Carcinoscorpius rotundicauda); DmTep (NP_523578.1, Drosophila melanogaster); DpTep (EFX86067.1, Daphnia pulex); EbCD109, EbC3 (BAD12264.1, P98094.1, Eptatretus burgeri); EsC3 (ACF04700.1, Euprymna scolopes); FcA2M (ABP97431.1, Fenneropenaeus chinensis); GgC3 (U16848.1, Gallus gallus); HaA2M, HaC3–1, HaTep (AB622470.1, AB622468.1, AB622471.1, Hasarius adansoni); HlCD109 (AB481386.1, Haliplanella lineata); HsA2M, HsCD109, HsCPAMD8, HsC3, HsPZP (P01023.3, NP_598000.2, NP_056507.2, NP_000055.2, CAA38255.1, Homo sapiens); IsTEP (XP_002409560.1, Ixodes scapularis); LsA2M (BAA19844.1, Limulus sp.); MmC3 (NM_009778.3, Mus musculus); OmA2M (AAN10129.1, Ornithodoros moubata) and TcPZP, TcCD109 (XP_008195453.1, XP_972838.2, Tribolium castaneum).