Figure 3

Quantitative predictions of iLME620. (A) Comparison of batch growth rates and in silico model predictions. (B) Comparison of batch fermentation end-product profiles and in silico model predictions; Exp: Experimental value, SIM: In silico simulation. (C) Comparison of in silico and experimentally observed by-product yields from glucose, xylose and pyruvate. (D) Effect of oxygen on the fermentative product profiles and the overall NAD(H) turnover rate as computed by flux-sum. Note that glucose uptake rate was constrained at 10 mmol gDCW−1 hr−1 for simulations used in Fig. 3C and D.