Figure 4 | Scientific Reports

Figure 4

From: miRNAs in bone tissue correlate to bone mineral density and circulating miRNAs are gender independent in osteoporotic patients

Figure 4

Relative expression of analyzed miRNAs in osteoclasts. Osteoclasts were generated from PBMCs isolated from blood samples of osteoporotic and non-osteoporotic patients. PBMCs were stimulated with M-CSF and RANKL for a period of 21 days or 28 days to generate the osteoclasts. The expression levels of miRNA-21-5p (A), miRNA-23a-3p (B), miRNA-24-3p (C), miRNA-93-5p (D), miRNA-100-5p (E), miRNA-122-5p (F), miRNA-124-3p (G), miRNA-125b-5p (H) and miRNA-148a-3p (I) are illustrated. Significant differences are indicated by *p < 0.05, **p < 0.01. Normality of the data was tested by D’Agostino Pearson test. Statistical analysis was performed by means of Kruskal-Wallis test corrected by Dunn’s test for multiple comparisons.

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