Table 2 Virucidal activity of various sPLA2s from different sources.
sPLA2 | IC50 (ng/ml) | CC50 or HC50 (ng/ml) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
HCV | DENV | JEV | SINV | FLUAV | SeV | VSNJV | HSV-1 | WST-1 | LDH | Haemolysis | |
CM-II-sPLA2 | 0.036a) | 0.31a) | 1.34a) | >10,000a) | >10,000a) | >10,000a) | 2,300a) | >10,000a) | >10,000 | >10,000 | >10,000 |
A. mellifera | 117 ± 43 | 183 ± 38 | 49 ± 13 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 |
S. violaceoruber | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 |
Bovine pancreas | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 |
Porcine pancreas | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 | >10,000 |
