Table 3 Inhibition of the virucidal activity of CM-II-sPLA2 by manoalide.

From: Broad-spectrum antiviral agents: secreted phospholipase A2 targets viral envelope lipid bilayers derived from the endoplasmic reticulum membrane

Virus

IC50 of CM-II-sPLA2 (ng/ml) treated with:

Fold difference

Manoalide

Control

HCV

6.0 ± 4.1

0.035 ± 0.005

171

DENV

18.4 ± 13.6

0.26 ± 0.02

71

  1. Data are presented as the average ± SEM (n = 2).
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