Figure 5 | Scientific Reports

Figure 5

From: β-Eudesmol, an oxygenized sesquiterpene, stimulates appetite via TRPA1 and the autonomic nervous system

Figure 5

The effect of subcutaneous administration of β-eudesmol on GVNA, food and water intake. (A) Representative recordings of GVNA in pylorus ligated rats administered 0.5% carboxymethylcellulose (CMC) or β-eudesmol (5 ppb) containing 0.5% CMC water by subcutaneous administration (s.c.). (B) Effects of subcutaneous administration (s.c.) of β-eudesmol on GVNA in rats (n = 5). (C) Food intake in rats given β-eudesmol (n = 10). Food intake in the control group is shown by an open bar in the graph (n = 10). (D) Mean food intake during experimental periods. (E) Water intake in rats given β-eudesmol. The control is shown by a white bar in the graph. (F) Mean water intake during experimental periods. Values are means ± SEM. Statistical differences were analyzed using the Mann-Whitney U test. *p < 0.05. n. s., not significant. CTL, control; β-EUD, β -eudesmol.

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