Figure 7 | Scientific Reports

Figure 7

From: Porphyromonas gingivalis lipopolysaccharides act exclusively through TLR4 with a resilience between mouse and human

Figure 7

Cytokine production in human whole blood cells challenged with LPS. Human whole blood cells were treated with different doses of UP Ec LPS, STD Pg LPS or UP Pg LPS (0 to 10,000 ng.mL−1) for 20 h. TNF-α, IL-6, and MCP-1 levels were measured by ELISA in culture supernatants. Comparisons between different treatments have been analyzed by two-way ANOVA test followed by a Dunnett’s test. Data are expressed as mean ± SEM (n = 3 per group). *p < 0.05, **p < 0.01, ***p < 0.001 compared to 0 ng.mL−1 LPS.

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