Table 1 Demographic and clinicopathologic characteristics in healthy controls and patients with breast cancer.

From: FSCN1 gene polymorphisms: biomarkers for the development and progression of breast cancer

Variable

Controls N = 222 (%)

Patients N = 316 (%)

p value

Age (years)

Mean ± S.D.

Mean ± S.D.

 
 

41.50 ± 14.96

53.09 ± 11.33

p < 0.05

Cigarette smoking

 No

217 (97.7)

315 (99.7)

 

 Yes

5 (2.3)

1 (0.3)

p < 0.05

Alcohol consumption

 No

209 (94.1)

297 (94.0)

 

 Yes

13 (5.9)

19 (6.0)

p > 0.05

Clinical stage

 I/II

 

243 (76.9)

 

 III/IV

 

73 (23.1)

 

Tumor size

 ≤T2

 

300 (94.9)

 

 >T2

 

16 (5.1)

 

Lymph node status

 N0 + N1

 

248 (78.5)

 

 N2 + N3

 

68 (21.5)

 

Distant metastasis

 M0

 

306 (96.8)

 

 M1

 

10 (3.2)

 

Histological grade

 G1 + G2

 

219 (69.3)

 

 G3

 

97 (30.7)

 

ER status

 Positive

 

96 (30.4)

 

 Negative

 

220 (69.6)

 

PR status

 Positive

 

146 (46.2)

 

 Negative

 

170 (53.8)

 

HER2

 Positive

 

199 (63.0)

 

 Negative

 

117 (37.0)

 
  1. The Mann-Whitney U-test and Fisher’s exact test were used to compare values between controls and patients with breast cancer. *p < 0.05 was statistically significant. ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.