Table 2 P. aeruginosa biomass reduction after primary neutrophils, MEM, and mAb treatment.

From: Anti-Psl Targeting of Pseudomonas aeruginosa Biofilms for Neutrophil-Mediated Disruption

 

Condition

% Biomass Reductiona

p-Valueb

vs. Control IgG

vs. mAb mixture

vs. MEM

mAb mixture

—

52.6 +/− 3.4

<0.001

—

—

MEM 0.5 µg/ml

−mAB

11.0 +/− 4.4

n.s.

<0.01

—

+mAB

52.9 +/− 6.2

<0.01

n.s.

<0.0001

MEM 3 µg/ml

−mAB

11.2 +/− 5.1

n.s.

<0.01

—

+mAB

60.3 +/− 5.9

<0.01

n.s.

<0.0001

MEM 30 µg/ml

−mAB

29.2 +/− 9.2

n.s.

n.s.

—

+mAB

70.0 +/− 3.3

<0.001

<0.01

<0.05

  1. aCompared to IgG control treated biofilms +/−SEM.
  2. bn.s. means not significant with p-Value > 0.05.
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