Table 3 Summary statistics of SUVr and Centiloid scores in disease-specific cortical target regions from each of five reference regions

From: Centiloid method evaluation for amyloid PET of subcortical vascular dementia

  

SUVr

Centiloid score

Bartlett’s statistic

 

CG

WC

WC + B

Pons

WM

CG

WC

WC + B

Pons

WM

AD

Patient

Mean

2.457

2.073

1.973

1.571

1.219

100.000

100.000

100.000

100.000

100.000

 

SD

0.445

0.335

0.307

0.234

0.107

33.643

30.708

29.525

28.065

21.001

12.685*

YC

Mean

1.135

0.981

0.933

0.739

0.709

0.000

0.000

0.000

0.000

0.000

 

SD

0.054

0.049

0.049

0.062

0.054

4.097

4.500

4.743

7.393

10.616

45.891*

Effect size

3.698

4.043

4.200

4.363

5.543

      

SVaD

Patient

Mean

2.368

1.997

1.896

1.496

1.220

100.000

100.000

100.000

100.000

100.000

 

SD

0.476

0.383

0.360

0.305

0.147

39.715

38.856

38.507

41.535

30.042

2.531

YC

Mean

1.169

1.011

0.961

0.761

0.730

0.000

0.000

0.000

0.000

0.000

 

SD

0.058

0.051

0.051

0.062

0.053

4.847

5.212

5.461

8.428

10.732

33.244*

Effect size

3.851

3.928

3.957

3.615

4.721

      
  1. AD: Alzheimer’s disease; SVaD: subcortical vascular dementia; SUVr: standardized uptake value ratio; CG: cerebellar gray; WC: whole cerebellum; B: brainstem; WM: white matter; SD: standard deviation; YC: young control; Asterisk(*): significant difference based on Bartlett’s statistics among five reference ROIs; Effect sizes were calculated using Cohen’s d with pooled standard deviation (See Eq. 2).